RTKs & Signal Transduction

Clathrin Mediated Receptor Endocytosis    |    Janet Iwasa

Dynamics of Lck in the T cell synapse – Upon T cell activation, clusters of signaling proteins form microdomains in the cell membrane. Some proteins, like the tyrosine kinase Lck (white) can freely diffuse between these clusters. Interactions between Lck and proteins in the signalling cluster can cause Lck to become immobilized.

» View the animation

Yeast Mating Pathway    |    Janet Iwasa

A 3D nimation depicting the step by step signaling transduction process of the mating pathway in yeast.

» View the animation