Drug / Mechanism of Action

Penicillin and Antibiotic Resistance    |    Maria Voigt

This animation provides a detailed explanation for how penicillin and penicillin-related antibiotics disrupt the bacterial life cycle, as well as the underlying molecular mechanisms by which bacteria develop resistance.

» View the animation at RCSB PDB

Rapamycin, FKBP12 & FRAP    |    Biointeractive.org, Eric Keller

Dimerization of FKBP12 & FRAP is shown upon binding of the small molecule rapamycin.

» View the animation

DNA Nanorobot (Wyss)    |    Digizyme

This animation depicts the structure and function of a drug delivery device created entirely of DNA. The therapeutic payload (in this case antibodies) is protected from the environment until a target protein (in this case PDGF, in green) competes for binding of the aptamer latches and triggers opening of the clamshell-like device.

» View the animation