Cytoskeleton / Molecular Motors

Fantastic Vesicle Traffic    |    Daniel von Wangenheim

How do plant cells deliver new material to their growing root hair tip? A combination of time-lapse photography, fluorescence live cell imaging and animation shows the molecular mechanisms in the context of the entire organism.

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Myosin Mechanism    |    Graham Johnson

This animation describes the translation of chemical bond energy of ATP into the sliding motion of thick/thin filaments in our muscle fibers.

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Microtubules: Structure, Function & Dynamics    |    Geordie Martinez, Steve Davy, Stylus Visuals

This Maya animation depicts the dynamic self-assembly and dissassembly processes of microtubules. The animation incoporates atomic resolution structural information for tubulin (as it undergoes a GTP vs GDP-induced conformational change), as well as cryoEM data for ‘protofilament peels’ and ‘helical ribbons’ from the Nogales lab.

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Kinesin Mechanism    |    Graham Johnson

Kinesin walking along a microtubule protofilament demonstrating how energy exchanges combine with binding events to create forward motion.

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Cell Quakes – Actin & Actinin    |    Anthony Zielinksi, Charles Lumsden

This movie presents a simulation of the behavior of selected cytoskeletal components as external forces are applied to the model (representing the forces of cell migration).

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