Pathways database, manually curated, peer-reviewed database of biomolecular pathways.
these databases can be used to determine if two or more proteins interact with one another in a cellular environment. This interaction data does not replace the need for confirmation of protein function from primary literature.
KEGG Pathway Maps
KEGG Pathway Maps is a resource for common signaling pathway maps. It can be used as a “first stop” for reviewing a signaling pathway of interest. Signaling pathways are often the basis for telling a story about a molecule (or molecules) of interest in a molecular visualization.
CST pathways is a resource for common signaling pathway maps. It can be used as a “first stop” for reviewing a signaling pathway of interest. Signaling pathways are often the basis for telling a story about a molecule (or molecules) of interest in a molecular visualization.
PathwayLinker is a resource for visualizing signaling pathways that integrates data from three signaling pathway databases. The user can query a protein of interest to determine its interaction partners and to view a more complete picture of the signaling pathways the protein is part of. This information can help to create a story for the “life” of the protein in a molecular visualization.
The Uniprot database can be used to find protein sequence and functional information. The information in this database can be combined with 3D structural data to determine the function of the whole protein as well as different domains of the protein. This information can be used to determine, for example, the regions of a membrane protein that are present inside or outside a cell, or the region of a protein that binds to DNA.
Human Protein Interactome
The Human Protein Interactome is a database for human protein-protein interactions. This database can be used to determine what other proteins a protein of interest binds to and interacts with, which hints at the function of that protein. After using abundance data to determining which components to include in the environment of a molecular landscape, this database can be used to determine which components should interact with one another.